POISONOUS PARTS: Seeds. TOXIC IF EATEN IN LARGE QUANTITIES. Symptoms include respiratory depression and slow heartbeat, sleepiness, convulsions. Toxic Principle: Alkaloids such as lupinine, anagyrine, sparteine, and hydroxylupanine. (Poisonous Plants of N.C.)
The ingestion of 3 grams of lupin seeds per month for 8 years was associated with the development of motor neuron disease (spasticity and amyotrophy) such as seen with Lathyrus. Eating the seeds in large quantities can be fatal to humans or animals. Lupine alkaloids are not lost or detoxified when the plant is dried. (Ferris, H.)
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